It is just 100 years since Marchand [1] identified choriocarcinoma as a tumour arising from placental villous trophoblast. Earlier description of similar tumours failed to identify their tissue of origin. Gestational Trophoblastic Disease (GTD) is the terminological umbrella now used to span the spectrum of cellular proliferations ranging from villous forms of hydatiform mole through invasive m...

background: gestational trophoblastic disease (gtd) defines a heterogenenous group of interrelated lesions that arise from the trophoblastic epithelium of the placenta. there are several histologically distinct types of gtd: hydatiform mole (complete or partial), persistant/invasive gestational trophoblastic neoplasia (gtn), choriocarcinoma and placenta site trophoblastic tumors. the aim of thi...

the result of the 6 years study of patients with hydatiform mole (hm) and its malignant degeneration in isfahan are presented. the over all frequency is estimated to be one hm in 440 child births. this frequency has remained relatively unchanged through out the study. increased consumption of meet did not seem to lower the frequency of hydatiform mole in our study. the over all frequency of mal...

The hydatiform mole is a gestational trophoblastic disease caused by abnormal gametogenesis and fertilization. The incidence is rare in our country. It seems to be encourage by poor nutrition in beta carotene, consanguinity, to early or to old maternal age, abortion history, endocrine problems, dysfunctions of genital organs, genital disorders. It is frequent between the 11th and 25th week of p...

The present case study is on a 16-year-old woman who was suffering from nephrotic syndrome after recovery from complete type of hydatiform mole. She was admitted in hospital because of proteinurea and hematuria. Then she was showing a generalized edema compatible with neprhotic syndrome. In her past medical history she had a suction curettage for hydatiform mole. After she received 4 courses ch...

estational trophoblastic disease includes following forms of growth disturbance of the human trophoblast: hydatiform mole, invasive mole, choriocarcinoma and placental site trophoblastic tumors. Term gestational trophoblastic disease is applied to the letter three conditions. Diagnosis and decision to institute treatment are sometimes undertaken without histopathological finding. Gestational tr...